Lost Bubble's gameplay is fairly standard for the genre. Using a bubble-firing magic wand at the base of the screen, players fire bubbles towards a predefined arrangement at the top in an attempt to cause a "Pandora's Box" special item to fall.

Connecting three or more bubbles of the same color causes them to pop and disappear, and if this causes an arrangement of bubbles to no longer be connected to the top of the screen, they fall to the bottom and turn into collectible coins and point-scoring stars.

Players have a limited number of bubbles with which to complete each level, and they also fail if they hit Pandora's Box with a bubble — something which the game doesn't make clear until after it has happened for the first time.

Lost Bubble is a solid, if rather unremarkable, example of a bubble shooter. It plays well, runs smoothly and has the potential to monetize well, particularly given the number of users it has been picking up recently.