Former enemies and rivals begin to band together as New York's villains realize the potential of Iso-8. And the more you learn about who's really pulling the strings, the more all signs point to Latveria.

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Mission 1 - Sacred Ground

Sacred Ground
Mastery and Recommended Levels
	Level 15
- 9,000 points	Level 17
- 198,000 points	Level 19
- 396,000 points	Level 21
- 792,000 points	Level 23
- 1,584,000 points	Level 25

Unlock Requirements:

• 1 Star Mastery in Chapter 2 - Mission 5
• Acquire a total of 15 Mastery Stars
• Recruit 6 Heroes.

Location: St. Patrick's Cathedral

Team-Up: Luke Cage

Battles

• Low: x3
• Medium: x1
• High: x2

Enemies

• Servo-Minion
• Servo-Pummeler
• Servo-Soldier
• Servo-Basher
• Servo-Driller
• Servo-Miner

Mini-Boss: Minimum Cleared: 1

• Servo-Pummeler
• Vapor
• Servo-Driller

Boss: Minimum Cleared: 5

• Wave 1: Servo-Minion, Servo-Miner
• Wave 2: Whiplash

Boss Drops:

• Cryo-Tonfa
• Assault Shotgun

Deploy Missions

• Requirement: Iron Fist
• Duration: 2 Battles
• Requirement: Any Scrapper
• Duration: 1 Battle
• Requirement: Any Hero
• Duration: 2 Battles

Mission 2 - Brooklyn Bridge is Falling Down

Brooklyn Bridge is Falling Down
Mastery and Recommended Levels
	Level 16
- 9,000 points	Level 18
- 211,000 points	Level 20
- 442,000 points	Level 22
- 844,000 points	Level 24
- 1,688,000 points	Level 26

Unlock Requirements:

• 1 Star Mastery in Mission 1

Location: Brooklyn Bridge

Team-Up: Thing

Battles

• Low: x1
• Medium: x3
• High: x2

Enemies

• Maggia Grunt
• Maggia Henchman
• Maggia Hitman
• Maggia Bodyguard
• Maggia Gunman
• Maggia Duelist

Mini-Boss: Minimum Cleared: 2

• Maggia Duelist
• Boomerang

Boss: Minimum Cleared: 3

• Wave 1: Maggia Bodyguard, Maggia Grunt
• Wave 2: Hydro-Man

Boss Drops:

• Tidal Fist
• NF3000

Deploy Missions

• Requirement: Any Scrapper
• Duration: 3 Battles
• Requirement: Invisible Woman
• Duration: 2 Battles
• Requirement: Any Hero
• Duration: 1 Battles

Mission 3 - RAID-ical Resolution

RAID-ical Resolution
Mastery and Recommended Levels
	Level 17
- 9,000 points	Level 19
- 216,000 points	Level 21
- 432,000 points	Level 23
- 864,000 points	Level 25
- 1,728,000 points	Level 27

Unlock Requirements:

• 1 Star Mastery in Mission 2
• Find 4 Skeleton Keys (randomly drop in Mission 2 battles)
• Own and Staff 4 Jets on the Flight Deck

Location: UN Building

Team-Up: War Machine

Battles

• Low: x1
• Medium: x2
• High: x3

Enemies

• Bioterrorist
• Physicist
• Commander

Mini-Boss: Minimum Cleared: 3

• Wave 1: Bioterrorist, Physicist, Bioterrorist
• Wave 2: Bulldozer

Team-Up: War Machine (optional)

Boss: Minimum Cleared: 4

• Fixer
• Physicist

Boss Drops:

• D.A.R.S. Suppressor
• S.A. "Siege"

Deploy Missions

• Requirement: Any Hero
• Duration: 1 Battle
• Requirement: Any Bruiser
• Duration: 1 Battle
• Requirement: Iron Man
• Duration: 2 Battles

Mission 4 - Odd Bedfellows

Odd Bedfellows
Mastery and Recommended Levels
	Level 18
- 7,000 points	Level 20
- 206,000 points	Level 22
- 412,000 points	Level 24
- 824,000 points	Level 26
- 1,648,000 points	Level 28

Unlock Requirements:

• 1 Star Mastery in Mission 3

Team-Up: Kitty Pryde

Battles

• Low: x2
• Medium: x2
• High: x2

Enemies

• Iapetos Sentinel
• Themis Sentinel
• Phoebe Sentinel
• Crius Sentinel
• Hyperion Sentinel
• Rhea Sentinel
• Coeus Sentinel
• Cronus Sentinel

Mini-Boss: Minimum Cleared: 2

• Wave 1: Iapetos, Themis Sentinel, Iapetos Sentinel
• Wave 2: Toad

Boss: Minimum Cleared: 5

• Sabretooth

Boss Drops:

• Offensive Accelerator
• Fang-L13

Deploy Missions

• Requirement: Colossus
• Duration: 2 Battles
• Requirement: Any Infiltrator
• Duration: 1 Battle
• Requirement: Any Hero
• Duration: 2 Battle

Mission 5 - Three Strikes

Three Strikes
Mastery and Recommended Levels
	Level 19
- 8,500 points	Level 21
- 333,000 points	Level 23
- 666,000 points	Level 25
- 1,332,000 points	Level 27
- 1,332,000 points	Level 29

Unlock Requirements:

• 1 Star Mastery in Mission 4
• Find 6 Mini Disks (randomly drop in Mission 4 battles)

Location: Yankee Stadium

Team-Up: Hawkeye

Battles

• Low: x2
• Medium: x2
• High: x1

Enemies

• Muscle
• Framer
• Mad Dog
• Bullets
• Slicer
• Enforcer

Mini-Boss: Minimum Cleared: None

• Bullets
• Vulture
• Mad Dog 

Minimum Cleared: 2

• Wave 1: Lead Foot, Ice Pick, Lead Foot
• Wave 2: Sandman

Boss: Minimum Cleared: 6

• Green Goblin

Boss Drops:

• D.A.R.S. Suppressor
• Curative Reach

Deploy Missions

• Requirement: Black Widow
• Duration: 1 Battle
• Requirement: Any Blaster
• Duration: 1 Battle
• Requirement: Any Tactician
• Duration: 2 Battles
• Requirement: Spider-Man
• Duration: 2 Battles

Epic Boss

Must finish ALL battles and deploys before the Epic Boss will appear

• Dr. Doom

Boss Drops:

• The Doombringer

Premium Mission: Cephalocarrier

Cephalocarrier
Mastery and Recommended Levels
	Level 20
- 10,500 points	Level 22
- 244,000 points	Level 24
- 488,000 points	Level 26
- 976,000 points	Level 28
- 1,952,000 points	Level 30

Unlock Requirements:

• Recruit Spider-Man

Location: USS Intrepid

Team-Up: Spider-Man

Battles

• Low: x3
• Medium: x2
• High: x2

Enemies

• Maggia Henchman
• Maggia Grunt
• Maggia Thug
• Maggia Gunman
• Maggia Duelist
• Maggia Bodyguard
• Maggia Captain
• Maggia Assassin
• Maggia Hitman

Mini-Boss: Minimum Cleared: 5

• Maggia Duelist
• Madame Masque
• Maggia Thug

Minimum Cleared: 5

• Wave 1: Maggia Grunt, Maggia Gunman, Maggia Grunt
• Wave 2: Maggia Thug, Hammerhead

Boss: Minimum Cleared: 8

• Doctor Octopus

Boss Drops:

• Web Blaster
• Galvanic Arm

Deploy Missions

• Requirement: Hawkeye
• Duration: 2 Battles
• Requirement: Any Scrapper
• Duration: 1 Battle
• Requirement: Any Hero
• Duration: 2 Battles
• Requirement: Spider-Woman
• Duration: 1 Battle